Those Wonder Working Enzymes: Healing in Depth

by Deep, Radi, and Mithu on June 17, 2010

in Natural Health Supplements

Having read about the many health benefits of systemic enzymes, and experienced some of their powerful healing effects first hand, we felt we had to share this information with all our readers.

To briefly mention some of our personal experiences with enzymes, Mithu’s painful knee and tender ankle that caused her to hobble rather than walk were both healed in a very short time after starting a course of serrapeptase enzyme. Radi, who in her ignorant past used to take powerful NSAIDS to reduce her back pain, now pops an enzyme instead for safe and lasting relief.  She has even found enzymes an effective and natural pain reliever for a troublesome tooth. We are convinced and hope you will find the information below both interesting and useful.


In the eighteenth and nineteenth centuries, the digestion of meat by stomach acids and the conversion of starch into sugars by saliva and plant extracts were known about, but  the mechanisms responsible for these processes had not yet been identified.

In the nineteenth century, Louis Pasteur, studying the action of yeast in the fermentation of sugar into alcohol, concluded that it was catalyzed by a force contained in yeast cells called “ferments.”

In 1877, the German physiologist Wilhelm Kühne used the term “enzyme” from the Greek “zymosis,” which means “to leaven,” to describe the process of fermentation.

The term “enzyme” was used later when referring to non-living substances such as pepsin, and the term “ferment” to chemical activity produced by living organisms.

Role of Enzymes:

Enzymes act as catalysts in living organisms regulating the rate at which chemical reactions proceed, without being altered in the process. They reduce the activation energy needed to start these reactions – without them the chemical reactions would be too slow to sustain life as we know it. Our bodies contain about 3000 enzymes resulting in 25,000 to 30,000 enzymatic reactions.

Digestive enzymes act in the stomach to aid digestion of food while systemic enzymes (the word “systemic” means “body-wide”) are metabolic enzymes that operate not just in digestion, but throughout the body in all organs and systems. Most systemic enzymes are proteases (or proteolytic enzymes), regulating protein function and aiding the digestion of those proteins that are no longer needed or are even harmful in the body. We will be concentrating on systemic enzymes in this article because of their outstanding therapeutic value.

Natural Anti-Inflammatory:

Inflammation is an immune system reaction to irritation or injury in the body. It creates a protein chain called a Circulating Immune Complex (CIC) tagged for a specific site. This CIC travels down to the targeted area causing pain and swelling. At first, by drawing our attention to a hurt part of the body, this is a beneficial reaction, but because it is self-perpetuating, it becomes an irritant in itself causing further CIC production.

Anti-inflammatory drugs inhibit the formation of all CICs despite the fact that some, such as those that keep the kidneys functioning or maintain intestinal lining, are vital to life. The non-steroidal anti-inflammatory drugs (NSAIDs) are also highly toxic to the liver.

Opposed to these harmful drugs are systemic enzymes, which are safe and free from dangerous side effects. They have no toxic dose and, very importantly, can tell the difference between helpful and excessive CICs. Because hydrolytic enzymes are “lock and key” mechanisms, their “teeth” will only fit over bad CICs and “eat” them. Thus, inflammation and pain are considerably lowered in the whole system.


Fibrosis is scar tissue and enzymes particularly enjoy a scar tissue meal! Our bodies produce a finite amount of enzymes in our lifetime and we use up a very large amount of our stores by the time we are 27 years old. From then on, the body becomes extremely stingy in dealing out enzymes, in order to prolong our lives so our repair systems have no way of reducing the overabundance of fibrin deposited everywhere, from simple cuts to the insides of our organs and blood vessels. They can reduce the size and function of internal organs over time and can result in various conditions such as women’s ailments (uterine fibroids, endometriosis, and fibrocystic breast disease), arterial sclerotic plaque etc.

All of these effects can be controlled and reduced by replacing the necessary enzymes. Even old scar tissue from surgical wounds, fibrosis of the lungs, renal fibrosis, and even keloids, can be “eaten” away by enzymes many years after their formation. This is a fact known in Europe and Japan, where orally administered enzymes have been clinically used for over 40 years.

Blood Cleansing:

Cells and organs dispose of their garbage (dead matter and waste products) through the blood. Excess fibrin can thicken the blood and cause clot formation. All this waste is supposed to be cleaned up by the liver but given the toxic condition of our overworked livers due to unhealthy lifestyles, this process can take days and sometimes even weeks.

Systemic enzymes can take the strain off the liver by ridding the blood of excess fibrin and reducing the stickiness of blood cells, which are the two main factors in strokes and heart attacks due to blood clots. Enzymes also help out by breaking down dead material to be passed immediately into the bowel.

They cleanse the FC receptors in white blood cells, thus improving their function and availability in fighting infection.  Here, we have to slip in a word of caution. Hemophiliacs and those on a prescription of blood thinners should not use systemic enzymes without direct medical supervision. This is because there is a possibility of thinning the blood too much.

Autoimmune Illnesses:

With a depressed immune system, our bodies become vulnerable to infections and disease, but an overactive immune system creates antibodies that attack the body’s own tissues. Examples are autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and lupus. Enzymes being adaptogenic seek to restore the body’s equilibrium. They tone down the immune function and “eat” inappropriate antibodies.

Viral, Bacterial, and Fungal Infections:

A virus in order to replicate in our bodies has to bond itself to the DNA in our cells through the medium of the exterior protein cell wall. Enzymes recognize the proteins that are foreign in the blood and inhibit viral replication through their “lock and key” mechanism (mentioned earlier), thus rendering individual viruses inert. In vitro studies have shown the promising effects of systemic enzymes on viral, bacterial, and fungal organisms.

Inflammation: Parkinson’s, Alzheimer’s, Chronic Fatigue, Autism etc.

It is known today that the many degenerative changes in the brain of an Alzheimer’s patient are due to medically detected moderate inflammation of that organ. Similarly, a link has been found between subclinical brain inflammation and Parkinson’s. In Europe, the name officially used for chronic fatigue syndrome is “myalgic encephalomyelitis” which is muscle pain caused by brain swelling.

Autism too could be due to brain swelling. Its cause is still under debate but many doctors feel it is caused by the mercury in childhood inoculations. Flu shots for adults have the same mercury preservative and some doctors feel that five or more flu shots could trigger Alzheimer’s Disease. Other doctors feel that inflammation could be due to the viruses in the vaccines even though they are weakened versions of live viruses. Well, conclusions will be reached sooner or later.

New studies are even implicating brain inflammation with mental depression.

Internal chronic inflammation increases with age and medical science has now realized that this condition is the root cause of many serious diseases ranging from cancer and diabetes to heart disease. This is because of the lowered production of proteolytic enzymes so the only anti-inflammatory substances that we can safely take, long term, are systemic enzymes.

Serrapeptase Enzyme:

Having discussed the very valuable therapeutic effects of systemic enzymes in general, we would now like to bring your attention to a particularly potent enzyme, serrapeptase. The search for a superior enzyme offering safe and powerful anti-inflammatory properties led to the discovery of serrapeptase in the early 1970s. It was originally found in the silk worm where it is naturally present in its intestine. This enzyme melts a hole out of the cocoon, thus enabling the moth to emerge unharmed. We marvel at the intelligence in Nature that targets dead or inappropriate tissue without harming the whole. Now, however, serrapeptase produced commercially through fermentation.

Serrapeptase is enteric coated to pass safely into the intestines from where it is transported through the circulatory system to cells and tissues throughout the body. As we noted earlier, it has the ability to dissolve avital tissue without damaging living cells.  Its anti-inflammatory effects have been found to be superior to those of other proteolytic enzymes, and among other conditions, it has been used to treat chronic sinusitis, , traumatic injuries, post operative inflammation, cystitis, epididymitus, and for the elimination of bronchopulmonary secretions .

Unlike other biological enzymes, serrapeptase affects only non-living tissue such as old fibrous layers that narrow the lining of our arteries, restricting oxygen and blood flow to the brain. It became widely known after Dr. Hans Nieper, a German doctor, used it to treat arterial blockage in his heart patients. Dr. Nieper described the amazing and quick recovery without surgery of two patients – a woman scheduled to have her hand amputated and a man scheduled for bypass surgery – after being treated with serrapeptase.

Some Final Cautions:

In case our readers get carried away by the dramatic effects of systemic enzymes, we would like to add a few cautionary notes regarding people who should not use enzyme therapy except under strict medical supervision.

  1. Individuals taking prescription blood thinners such as Coumadin, Heparin, and Plavix.
  2. Hemophiliacs.
  3. Anyone who is scheduled for surgery in less than two weeks.
  4. Individuals with known ulcers of the stomach.
  5. Individuals with gastroesophageal reflux disease (GRD).
  6. Pregnant or lactating women.
  7. Individuals currently taking antibiotics.
  8. Individuals with allergic reactions to pineapple and papaya (the sources of two common proteolytic enzymes – bromelain and papain).

Please Note: For more information on our recommended source of powerful therapeutic serrapeptase products for people and pets, please visit Serra Enzyme: A Miracle Healer and Pain (and Inflammation) Reliever

Key Reference Sources:

  • Dr. H.A. Nieper. “Silk Worm Enzymes for Carotid Artery Blockage” (http://www.serrapeptase.info/)
  • http://www.answers.com/topic/enzyme
  • Dr. William Wong. “What Are Systemic Enzymes And What Do They Do?” (http://www.enzymescience.com/index.htm)
  • http://www.serrapeptase.info/
  • http://www.staytuned.ws/systemic_enzymes.html
  • http://en.wikipedia.org/wiki/Enzyme

Disclaimer: The information contained in this website is only intended to educate and inform our readers. It is in no way intended to provide medical advice or to diagnose or treat any disease. If you have a health problem, you should consult a healthcare practitioner before taking any substances for medicinal purposes.

1 Comment

  • At 2010.09.17 14:47, Naturopathic Treatment said:

    An apple a day to keep the doctor away. Nice name for the site. The content here is a real gem well detailed and on point. Loved the site.

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